Saturday, March 7, 2020

OUR LADY OF LA SALETTE ON COV-19: On The Origin And Continuing Evolution Of SARS-CoV-2


There will be bloody wars and famines, plagues and infectious diseases.Our Lady of La Salette 19 Sept. 1846 (Published by Mélanie 1879)

“The earth will be struck by calamities of all kinds (in addition to plague and famine which will be wide-spread). Our Lady of La Salette 19 Sept. 1846 (Published by Mélanie 1879)

ABSTRACT 
The SARS-CoV-2 epidemic started in late December 2019 in Wuhan, China, and has since impacted a large portion of China and raised major global concern. Herein, we investigated the extent of molecular divergence between SARS-CoV-2 and other related coronaviruses. Although we found only 4% variability in genomic nucleotides between SARS-CoV-2 and a bat SARS-related coronavirus (SARSr-CoV; RaTG13), the difference at neutral sites was 17%, suggesting the divergence between the two viruses is much larger than previously estimated. Our results suggest that the development of new variations in functional sites in the receptor-binding domain (RBD) of the spike seen in SARS-CoV-2 and viruses from pangolin SARSr-CoVs are likely caused by mutations and natural selection besides recombination. Population genetic analyses of 103 SARS-CoV-2 genomes indicated that these viruses evolved into two major types (designated L and S), that are well defined by two different SNPs that show nearly complete linkage across the viral strains sequenced to date. Although the L type (~70%) is more prevalent than the S type (~30%), the S type was found to be the ancestral version. Whereas the L type was more prevalent in the early stages of the outbreak in Wuhan, the frequency of the L type decreased after early January 2020. Human intervention may have placed more severe selective pressure on the L type, which might be more aggressive and spread more quickly. On the other hand, the S type, which is evolutionarily older and less aggressive, might have increased in relative frequency due to relatively weaker selective pressure. These findings strongly support an urgent need for further immediate, comprehensive studies that combine genomic data, epidemiological data, and chart records of the clinical symptoms of patients with coronavirus disease 2019 (COVID-19). Source

“The great chastisement will come, because men will not be converted; yet it is only their conversion that can hinder these scourges. God will begin to strike men by inflicting lighter punishments in order to open their eyes; then He will stop, or may repeat His former warnings to give place for repentance. But sinners will not avail themselves of these opportunities; He will, in consequence, send more severe castigations, anxious to move sinners to repentance, but all in vain. Finally, the obduracy of sinners shall draw upon their heads the greatest and most terrible calamities. Mélanie

“We are all guilty! Penance is not done, and sin increases daily. Those who should come forward to do good are retained by fear. Evil is great. A moderate punishment serves only to irritate the spirits, because they view all things with human eyes. God could work a miracle to convert and change the aspect of the earth without chastisement. God will work a miracle; it will be a stroke of His mercy; but after the wicked shall have inebriated themselves with blood, the scourge shall arrive Mélanie

“What countries shall be preserved from such calamities? Where shall we go for refuge? I, in my turn, shall ask, What is the country that observes the commandments of God? What country is not influenced by human fear where the interest of the Church and the glory of God are at stake? (Ah, indeed! What country, what nation upon earth?) In behalf of my Superior and myself, I have often asked myself where we could go for refuge, had we the means for the journey and for our subsistence, on condition that no person were to know it? But I renounce these useless thoughts. We are very guilty! In consequence of this, it is necessary that a very great and terrible scourge should come to revive our faith, and to restore to us our very reason, which we have almost entirely lost. Mélanie

MARIA OF THE CROSS,
Victim of Jesus nee MELANIE CALVAT,
Shepherdess of La Salette

"I protest highly against a different text, which people may dare publish after my death. I protest once more against the very false statements of all those who dare say and write First that I embroidered the Secret; second, against those who state that the Queen Mother did not say to transmit the Secret to all her people." Mélanie

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